TGF-β induces cholesterol accumulation to regulate the fate of tumor-derived extracellular vesicles

Lessons from Cancer: Unveiling the Role of Extracellular Vesicles

“TGF-β induces cholesterol accumulation to regulate the fate of tumor-derived extracellular vesicles”

Speaker: Dr. Dorival Mendes Rodrigues-Junior

Affiliation: Department of Medical Biochemistry and Microbiology, Uppsala University, Sweden

Date: Wednesday, February 5th, 2025

Time: 11:00 a.m. Estonian time (10:00 a.m. Swedish time)

Location: Online

Zoom Link: Join here

Speaker Bio: Dorival Mendes Rodrigues-Junior is a cancer researcher interested in elucidating signaling pathways promoting tumorigenesis driven by tyrosine kinase receptor activation (e.g., TGF-β and EGFR) and extracellular vesicles. He obtained a PhD in Molecular Biology in 2018 from the Federal University of São Paulo (Brazil) in collaboration with the National Cancer Centre of Singapore. Since 2020, Rodrigues-Junior has been working, first as a postdoctoral fellow, and now as a researcher in tumor biology at the Department of Medical Biochemistry and Microbiology at Uppsala University (Sweden). He is the current coordinator of the Swedish extracellular vesicles network (SweSEV).