Guest Lecture on Biological Sex’s Impact on Immunity by Dr. Camila Consiglio
On March 7, 2025, Camila presented her research on sex differences in human immunity using systems immunology. She explored how biological sex influences immune response, disease susceptibility, and treatment outcomes.
Key topics included:
Hormone Therapy Effects: Testosterone therapy increased inflammation and reduced antiviral responses, while estrogen therapy enhanced T-cell and NK cell activity.
Implications for Drug Development: Sex differences should be considered in vaccine and drug efficacy.
Extracellular Vesicles (EVs): Potential role of EVs in immune regulation and hormone therapy effects.
Future Research: Investigating EVs in hormone therapy, androgen receptor binding in immune cells, and vaccine response in gender-affirming therapy recipients.
The discussion emphasized the need for more inclusive research to improve treatment strategies for diverse populations.
